Complement Factor H Polymorphism in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of blindness in the elderly. We report a genome-wide screen of 96 cases and 50 controls for polymorphisms associated with AMD. Among 116,204 single-nucleotide polymorphisms genotyped, an intronic and common variant in the complement factor H ge...

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Main Authors: Klein, Robert J., Zeiss, Caroline, Chew, Emily Y., Tsai, Jen-Yue, Sackler, Richard S., Haynes, Chad, Henning, Alice K., SanGiovanni, John Paul, Mane, Shrikant M., Mayne, Susan T., Bracken, Michael B., Ferris, Frederick L., Ott, Jurg, Barnstable, Colin, Hoh., Josephine
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1512523/
https://ncbi.nlm.nih.gov/pubmed/15761122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1109557
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