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Severe cardiomyopathy in mice lacking dystrophin and MyoD

The mdx mouse, a mouse model of Duchenne muscular dystrophy, carries a loss-of-function mutation in dystrophin, a component of the membrane-associated dystrophin–glycoprotein complex. Unlike humans, mdx mice rarely display cardiac abnormalities and exhibit dystrophic changes only in a small number o...

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Auteurs principaux: Megeney, Lynn A., Kablar, Boris, Perry, Robert L. S., Ying, Chuyan, May, Linda, Rudnicki, Michael A.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC15120/
https://ncbi.nlm.nih.gov/pubmed/9874799
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