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A pharmacological profile of the novel, peripherally-selective κ-opioid receptor agonist, EMD 61753
1 The pharmacological properties of the novel diarylacetamide κ-opioid receptor agonist, EMD 61753, have been compared with those of ICI 197067 (a centrally-acting κ agonist) and ICI 204448 (a peripherally-selective κ agonist). 2 EMD 61753 binds with high affinity (IC(50) 5.6 nM) and selectivity (κ:...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1994
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1510549/ https://ncbi.nlm.nih.gov/pubmed/7889287 |
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