A pharmacological profile of the novel, peripherally-selective κ-opioid receptor agonist, EMD 61753

1 The pharmacological properties of the novel diarylacetamide κ-opioid receptor agonist, EMD 61753, have been compared with those of ICI 197067 (a centrally-acting κ agonist) and ICI 204448 (a peripherally-selective κ agonist). 2 EMD 61753 binds with high affinity (IC(50) 5.6 nM) and selectivity (κ:...

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Main Authors: Barber, A., Bartoszyk, G.D., Bender, H.M., Gottschlich, R., Greiner, H.E., Harting, J., Mauler, F., Minck, K.-O., Murray, R.D., Simon, M., Seyfried, C.A.
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510549/
https://ncbi.nlm.nih.gov/pubmed/7889287
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