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FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors.

1. ADP-dependent platelet aggregation is mediated by the P2T-purinoceptor and is specifically inhibited by ATP, which is a competitive P2T-purinoceptor antagonist. However, ATP functions as an agonist at other P2-purinoceptor subtypes in other tissues and is, therefore, non-selective. This paper des...

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Библиографические подробности
Главные авторы: Humphries, R G, Tomlinson, W, Ingall, A H, Cage, P A, Leff, P
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510445/
https://ncbi.nlm.nih.gov/pubmed/7858849
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