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Cardiovascular actions of the furoxan CAS 1609, a novel nitric oxide donor.

1. This study examines the cardiovascular effects of CAS 1609 (4-hydroxymethyl-furoxan-3-carboxamide) in vitro as well as in vivo in various animal models. 2. CAS 1609 relaxed guinea-pig pulmonary artery strips without endothelium with IC50-values of 0.9 microM (phenylephrine contracted) and 15 micr...

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Detalles Bibliográficos
Main Authors: Bohn, H, Brendel, J, Martorana, P A, Schönafinger, K
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510397/
https://ncbi.nlm.nih.gov/pubmed/7599929
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