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Increased striatal dopamine efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7-nitro indazole.

The role of nitric oxide (NO) in striatal dopamine release has been controversial. Most NO synthase inhibitors affect more than one isoform of the enzyme and exert vasoconstrictor effects which may also affect striatal dopamine function. We now report on the effect of a soluble monosodium salt of th...

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Bibliographic Details
Main Authors: Silva, M T, Rose, S, Hindmarsh, J G, Aislaitner, G, Gorrod, J W, Moore, P K, Jenner, P, Marsden, C D
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510264/
https://ncbi.nlm.nih.gov/pubmed/7533610
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