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Inhibition by dizocilpine (MK-801) of striatal dopamine release induced by MPTP and MPP+: possible action at the dopamine transporter.

1. The NMDA-type glutamate receptor antagonist, dizocilpine (MK-801) can protect against neurotoxicity associated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its principal metabolite, the 1-methyl-4-phenylpyridinium ion (MPP+). It has been suggested that these neurotoxic effects may...

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Sonraí Bibleagrafaíochta
Main Authors: Clarke, P B, Reuben, M
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1995
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510234/
https://ncbi.nlm.nih.gov/pubmed/7881731
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