Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis

Group B coxsackieviral (CVB) infection commonly causes viral myocarditis. Mice are protected from CVB3 myocarditis by gene-targeted knockout of p56(Lck)(Lck), the Src family kinase (Src) essential for T cell activation. Extracellular signal-regulated kinase 1 and 2 (ERK-1/2) can influence cell funct...

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Autors principals: Opavsky, Mary Anne, Martino, Tami, Rabinovitch, Marlene, Penninger, Josef, Richardson, Chris, Petric, Martin, Trinidad, Cathy, Butcher, Lisa, Chan, Janice, Liu, Peter P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151008/
https://ncbi.nlm.nih.gov/pubmed/12070303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13971
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