Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease

Older bone marrow transplantation (BMT) recipients are at heightened risk for acute graft-versus-host disease (GVHD) after allogeneic BMT, but the causes of this association are poorly understood. Using well-characterized murine BMT models we have explored the mechanisms of increased GVHD in older m...

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Main Authors: Ordemann, Rainer, Hutchinson, Raymond, Friedman, Jeffrey, Burakoff, Steven J., Reddy, Pavan, Duffner, Ulrich, Braun, Thomas M., Liu, Chen, Teshima, Takanori, Ferrara, James L.M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC150964/
https://ncbi.nlm.nih.gov/pubmed/11994414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14793
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