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Male infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1

Pseudophosphatases display extensive sequence similarities to phosphatases but harbor amino acid alterations in their active-site consensus motifs that render them catalytically inactive. A potential role in substrate trapping or docking has been proposed, but the specific requirements for pseudopho...

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Autors principals: Firestein, Ron, Nagy, Peter L., Daly, Megan, Huie, Phil, Conti, Marco, Cleary, Michael L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150957/
https://ncbi.nlm.nih.gov/pubmed/11994405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI12589
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