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Critical role for a high-affinity chemokine-binding protein in γ-herpesvirus–induced lethal meningitis

Chemokines are involved in recruitment and activation of hematopoietic cells in sites of infection and inflammation. The M3 gene of the γ-herpesvirus γHV68 encodes an abundant secreted protein that binds CC chemokines with high affinity. We report here that this gene is essential for efficient induc...

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Detalhes bibliográficos
Main Authors: van Berkel, Victor, Levine, Beth, Kapadia, Sharookh B., Goldman, James E., Speck, Samuel H., IV, Herbert W. Virgin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150927/
https://ncbi.nlm.nih.gov/pubmed/11927617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14358
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