TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

Angiotensin II (Ang II), a potent hypertrophic stimulus, causes significant increases in TGFb1 gene expression. However, it is not known whether there is a causal relationship between increased levels of TGF-β1 and cardiac hypertrophy. Echocardiographic analysis revealed that TGF-β1–deficient mice s...

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Main Authors: Schultz, Jo El J., Witt, Sandra A., Glascock, Betty J., Nieman, Michelle L., Reiser, Peter J., Nix, Stacey L., Kimball, Thomas R., Doetschman, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2002
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC150912/
https://ncbi.nlm.nih.gov/pubmed/11901187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14190
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