Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion

Mesangial cells maintain normal glomerular function by mediating ECM remodeling and immune complex disposal. We have recently identified megsin, a novel member of the serine protease inhibitor (serpin) superfamily predominantly expressed in the mesangium. While our previous studies suggested a role...

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Detalhes bibliográficos
Main Authors: Miyata, Toshio, Inagi, Reiko, Nangaku, Masaomi, Imasawa, Toshiyuki, Sato, Masahiro, Izuhara, Yuko, Suzuki, Daisuke, Yoshino, Atsusi, Onogi, Hiroshi, Kimura, Minoru, Sugiyama, Satoshi, Kurokawa, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150894/
https://ncbi.nlm.nih.gov/pubmed/11877466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14336
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