l-Type Amino Acid Transporter-1 Overexpression and Melphalan Sensitivity in Barrett's Adenocarcinoma

The L-type amino acid transporter-1 (LAT-1) has been associated with tumor growth. Using cDNA microarrays, overexpression of LAT-1 was found in 87.5% (7/8) of esophageal adenocarcinomas relative to 12 Barrett's samples (33% metaplasia and 66% dysplasia) and was confirmed in 100% (28/28) of Barr...

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Main Authors: Lin, Jules, Raoof, Duna A, Thomas, Dafydd G, Greenson, Joel K, Giordano, Thomas J, Robinson, Gregory S, Bourner, Maureen J, Bauer, Christopher T, Orringer, Mark B, Beer, David G
格式: Artigo
語言:Inglês
出版: Neoplasia Press Inc. 2004
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508631/
https://ncbi.nlm.nih.gov/pubmed/15068672
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