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15-Lipoxygenase-1 Expression Upregulates and Activates Insulin-Like Growth Factor-1 Receptor in Prostate Cancer Cells
We previously discovered that a fat-metabolizing enzyme, 15-lipoxygenase-1 (15-LO-1), is high in human prostate cancer (PCa) and correlates with disease progression. The biologic link between the aberrant 15-LO-1/linoleic acid (LA) metabolism and fat (which is a rich source of growth factors) in PCa...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Neoplasia Press Inc.
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1508629/ https://ncbi.nlm.nih.gov/pubmed/15068670 |
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