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Functional role of estrogen in pituitary tumor pathogenesis
Pituitary hyperplasia and lactotroph replication are induced by estrogen. The product of the pituitary tumor transforming gene (PTTG) exhibits in vitro and in vivo transforming activity and induces basic bFGF secretion, thereby modulating pituitary angiogenesis and tumor formation. We demonstrated p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150842/ https://ncbi.nlm.nih.gov/pubmed/11805140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14264 |
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