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Development of ichthyosiform skin compensates for defective permeability barrier function in mice lacking transglutaminase 1
Transglutaminase 1 (TGase 1) is one of the genes implicated in autosomal recessive congenital ichthyosis. Skin from TGase 1(–/–) mice, which die as neonates, lacks the normal insoluble cornified envelope and has impaired barrier function. Characterization of in situ dye permeability and transepiderm...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150837/ https://ncbi.nlm.nih.gov/pubmed/11805136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13563 |
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