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Development of ichthyosiform skin compensates for defective permeability barrier function in mice lacking transglutaminase 1

Transglutaminase 1 (TGase 1) is one of the genes implicated in autosomal recessive congenital ichthyosis. Skin from TGase 1(–/–) mice, which die as neonates, lacks the normal insoluble cornified envelope and has impaired barrier function. Characterization of in situ dye permeability and transepiderm...

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Detalhes bibliográficos
Main Authors: Kuramoto, Nobuo, Takizawa, Toshihiro, Takizawa, Takami, Matsuki, Masato, Morioka, Hiroyuki, Robinson, John M., Yamanishi, Kiyofumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150837/
https://ncbi.nlm.nih.gov/pubmed/11805136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13563
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