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A microfabricated device for sizing and sorting DNA molecules

We have demonstrated a microfabricated single-molecule DNA sizing device. This device does not depend on mobility to measure molecule size, is 100 times faster than pulsed-field gel electrophoresis, and has a resolution that improves with increasing DNA length. It also requires a million times less...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Chou, Hou-Pu, Spence, Charles, Scherer, Axel, Quake, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.11
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