Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

BAFF (BLyS, TALL-1, THANK, zTNF4) is a member of the TNF superfamily that specifically regulates B lymphocyte proliferation and survival. Mice transgenic (Tg) for BAFF develop an autoimmune condition similar to systemic lupus erythematosus. We now demonstrate that BAFF Tg mice, as they age, develop...

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Autors principals: Groom, Joanna, Kalled, Susan L., Cutler, Anne H., Olson, Carl, Woodcock, Stephen A., Schneider, Pascal, Tschopp, Jurg, Cachero, Teresa G., Batten, Marcel, Wheway, Julie, Mauri, Davide, Cavill, Dana, Gordon, Tom P., Mackay, Charles R., Mackay, Fabienne
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150825/
https://ncbi.nlm.nih.gov/pubmed/11781351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14121
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