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Acid incubation reverses the polarity of intercalated cell transporters, an effect mediated by hensin
Metabolic acidosis causes a reversal of polarity of HCO(3)(–) flux in the cortical collecting duct (CCD). In CCDs incubated in vitro in acid media, β-intercalated (HCO(3)(–)-secreting) cells are remodeled to functionally resemble α-intercalated (H(+)-secreting) cells. A similar remodeling of β-inter...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150817/ https://ncbi.nlm.nih.gov/pubmed/11781354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13292 |
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