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Natural selection of tumor variants in the generation of “tumor escape” phenotypes

The idea that tumors must “escape” from immune recognition contains the implicit assumption that tumors can be destroyed by immune responses either spontaneously or as the result of immunotherapeutic intervention. Simply put, there is no need for tumor escape without immunological pressure. Here, we...

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Detalhes bibliográficos
Main Authors: Khong, Hung T., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508168/
https://ncbi.nlm.nih.gov/pubmed/12407407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1102-999
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