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Thrombin-activatable fibrinolysis inhibitor (TAFI) deficiency is compatible with murine life

To investigate the consequence of deficiency in thrombin-activatable fibrinolysis inhibitor (TAFI), we generated homozygous TAFI-deficient mice by targeted gene disruption. Intercrossing of heterozygous TAFI mice produced offspring in the expected Mendelian ratio, indicating that transmission of the...

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Autors principals: Nagashima, Mariko, Yin, Zheng-Feng, Zhao, Lei, White, Kathy, Zhu, Yanhong, Lasky, Nina, Halks-Miller, Meredith, Broze, George J., Fay, William P., Morser, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150816/
https://ncbi.nlm.nih.gov/pubmed/11781355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI12119
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