DNA Damage Measured by the Comet Assay in Head and Neck Cancer Patients Treated with Tirapazamine

Tirapazamine (TPZ) [3-amino-1,2,4-benzotriazine 1,4-dioxide, SR4233, WIN 59075, and Tirazone(™)] is a novel anticancer drug that is selectively activated by the low oxygen environment in solid tumors. By killing the radioresistant hypoxic cells, TPZ potentiates the antitumor efficacy of fractionated...

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Detalhes bibliográficos
Main Authors: Dorie, Mary Jo, Kovacs, Mary S, Gabalski, Edward C, Adam, Markus, Le, Quynh-T, Bloch, Daniel A, Pinto, Harlan A, Terris, David J, Brown, J Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Stockton Press 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508108/
https://ncbi.nlm.nih.gov/pubmed/10933062
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