Chromosomal and Extrachromosomal Instability of the cyclin D2 Gene is Induced by Myc Overexpression

We examined the expression of cyclins D1, D2, D3, and E in mouse B-lymphocytic tumors. Cyclin D2 mRNA was consistently elevated in plasmacytomas, which characteristically contain Myc-activating chromosome translocations and constitutive c-Myc mRNA and protein expression. We examined the nature of cy...

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Detalhes bibliográficos
Main Authors: Mai, Sabine, Hanley-Hyde, Joan, Rainey, G Jonah, Kuschak, Theodore I, Paul, James T, Littlewood, Trevor D, Mischak, Harald, Stevens, Lisa M, Henderson, Darren W, Mushinski, J Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: Stockton Press 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508077/
https://ncbi.nlm.nih.gov/pubmed/10935479
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