A bcl-xS Adenovirus Selectively Induces Apoptosis in Transformed Cells Compared to Normal Mammary Cells

Oncogenes which drive the cell cycle, such as c-myc, can sensitize cells to apoptosis. This suggests the possibility that the expression of genes such as bcl-2 or bcl-xL is required to inhibit apoptosis induced by oncogene expression. We hypothesized that inhibition of Bcl-2/Bcl-xL by the pro-apopto...

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主要な著者: Sumantran, Venil N, Lee, David S, Woods Ignatoski, Kathleen M, Ethier, Stephen P, Wicha, Max S
フォーマット: Artigo
言語:Inglês
出版事項: Nature America, Inc. 2000
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1507566/
https://ncbi.nlm.nih.gov/pubmed/10935511
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