Common Interaction Surfaces of the Toll-Like Receptor 4 Cytoplasmic Domain Stimulate Multiple Nuclear Targets

Toll-like receptor 4 (TLR4) mediates the host response to lipopolysaccharide (LPS) by promoting the activation of pro- and anti-inflammatory cytokine genes. To activate each gene, numerous signal transduction pathways are required. The adaptor proteins MyD88 and TIRAP contribute to the activation of...

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Hlavní autoři: Ronni, Tapani, Agarwal, Vishal, Haykinson, Michael, Haberland, Margaret E., Cheng, Genhong, Smale, Stephen T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150739/
https://ncbi.nlm.nih.gov/pubmed/12640135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2543-2555.2003
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