Disruption of Mouse CD46 Causes an Accelerated Spontaneous Acrosome Reaction in Sperm

Human membrane cofactor protein (MCP, CD46) is a ubiquitously expressed protein known to protect cells from complement attack. Interestingly, when we examined the expression of mouse CD46, which we recently cloned, the message was found only in testis and the protein was found on the inner acrosomal...

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Main Authors: Inoue, Naokazu, Ikawa, Masahito, Nakanishi, Tomoko, Matsumoto, Misako, Nomura, Midori, Seya, Tsukasa, Okabe, Masaru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC150730/
https://ncbi.nlm.nih.gov/pubmed/12640142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2614-2622.2003
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