The ΔNp63α Phosphoprotein Binds the p21 and 14-3-3σ Promoters In Vivo and Has Transcriptional Repressor Activity That Is Reduced by Hay-Wells Syndrome-Derived Mutations

p63 is a recently identified homolog of p53 that is found in the basal layer of several stratified epithelial tissues such as the epidermis, oral mucosa, prostate, and urogenital tract. Studies with p63(−/−) mice and analysis of several human autosomal-dominant disorders with germ line p63 mutations...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Westfall, Matthew D., Mays, Deborah J., Sniezek, Joseph C., Pietenpol, Jennifer A.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2003
Subjects:	Transcriptional Regulation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150720/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.7.2264-2276.2003
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