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Use of Transgenic HLA A∗0201/Kb and HHD II Mice To Evaluate Frequency of Cytomegalovirus IE1-Derived Peptide Usage in Eliciting Human CD8 Cytokine Response

Unlike the pp65 protein of human cytomegalovirus (CMV), which has an immunodominant peptide, pp65(495-503), recognized by human CD8(+) cells in the context of HLA A∗0201, the fine peptide specificity for CMV IE1 has shown no such immunodominance. With the use of transgenic HLA A∗0201/Kb and HHD II m...

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Detalhes bibliográficos
Main Authors: Gallez-Hawkins, Ghislaine, Villacres, Maria C., Li, Xiuli, Sanborn, Margaret C., Lomeli, Norma A., Zaia, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150670/
https://ncbi.nlm.nih.gov/pubmed/12634406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4457-4462.2003
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