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Transcriptional Suppression of In Vitro-Integrated Human Immunodeficiency Virus Type 1 Does Not Correlate with Proviral DNA Methylation

Persistence of human immunodeficiency virus type 1 (HIV-1) constitutes a major obstacle in the control of HIV-1 infection. Here we investigated whether the CpG methylation of the HIV-1 promoter can directly influence the expression of the HIV-1 genome and thereby contribute to the persistence and la...

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Autors principals: Pion, Marjorie, Jordan, Albert, Biancotto, Angelique, Dequiedt, Franck, Gondois-Rey, Françoise, Rondeau, Sophie, Vigne, Robert, Hejnar, Jiri, Verdin, Eric, Hirsch, Ivan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150653/
https://ncbi.nlm.nih.gov/pubmed/12634362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4025-4032.2003
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