The Leader of Human Immunodeficiency Virus Type 1 Genomic RNA Harbors an Internal Ribosome Entry Segment That Is Active during the G(2)/M Phase of the Cell Cycle

The 5′ leader of the human immunodeficiency virus type 1 (HIV-1) genomic RNA contains highly structured domains involved in key steps of the viral life cycle. These RNA domains inhibit cap-dependent protein synthesis. Here we report that the HIV-1 5′ leader harbors an internal ribosome entry site (I...

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Detalhes bibliográficos
Main Authors: Brasey, Ann, Lopez-Lastra, Marcelo, Ohlmann, Theophile, Beerens, Nancy, Berkhout, Ben, Darlix, Jean-Luc, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150645/
https://ncbi.nlm.nih.gov/pubmed/12634354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.3939-3949.2003
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