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The CCR5 and CXCR4 Coreceptors Are Both Used by Human Immunodeficiency Virus Type 1 Primary Isolates from Subtype C

Human immunodeficiency virus type 1 (HIV-1) subtype C viruses with different coreceptor usage profiles were isolated from 29 South African patients with advanced AIDS. All 24 R5 isolates were inhibited by the CCR5-specific agents, PRO 140 and RANTES, while the two X4 viruses and the three R5X4 virus...

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Main Authors: Cilliers, Tonie, Nhlapo, Jabulani, Coetzer, Mia, Orlovic, Dragana, Ketas, Thomas, Olson, William C., Moore, John P., Trkola, Alexandra, Morris, Lynn
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC150635/
https://ncbi.nlm.nih.gov/pubmed/12634405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4449-4456.2003
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