Hepatitis C Virus NS3 ATPases/Helicases from Different Genotypes Exhibit Variations in Enzymatic Properties

The NS3 ATPase/helicase was isolated and characterized from three different infectious clones of hepatitis C virus (HCV). One helicase was from a genotype that normally responds to therapy (Hel-2a), and the other two were from more resistant genotypes, 1a (Hel-1a) and 1b (Hel-1b). Although the diffe...

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הוצא לאור ב:	J Virol
Principais autores:	Lam, Angela M. I., Keeney, David, Eckert, Patrick Q., Frick, David N.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2003
נושאים:	Replication
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12634355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.7.3950-3961.2003
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