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Cytoskeletal Requirements for Hepatitis C Virus (HCV) RNA Synthesis in the HCV Replicon Cell Culture System

Hepatitis C virus (HCV) induces microtubule aggregates in infected hepatocytes. To determine if cytoskeletal elements are important for HCV RNA synthesis, we examined the effect of cytoskeleton inhibitors on HCV replicon transcription in Huh7 cells. The data demonstrate that HCV replication complex-...

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Detalhes bibliográficos
Main Authors: Bost, Anne G., Venable, Daryl, Liu, Lifei, Heinz, Beverly A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150619/
https://ncbi.nlm.nih.gov/pubmed/12634397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.7.4401-4408.2003
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