Rapid Mutation Scanning of Genes Associated with Familial Cancer Syndromes Using Denaturing High-Performance Liquid Chromatography

Germline mutations in tumor suppressor genes, or less frequently oncogenes, have been identified in up to 19 familial cancer syndromes including Li-Fraumeni syndrome, familial paraganglioma, familial adenomatous polyposis coli and breast and ovarian cancers. Multiple genes have been associated with...

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Main Authors: Marsh, Deborah J, Theodosopoulos, George, Howell, Viive, Richardson, Anne-Louise, Benn, Diana E, Proos, Anné L, Eng, Charis, Robinson, Bruce G
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505599/
https://ncbi.nlm.nih.gov/pubmed/11494117
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