Interleukin 12 in Part Regulates Gamma Interferon Release in Human Whole Blood Stimulated with Leptospira interrogans

Heat-killed pathogenic Leptospira interrogans serovar rachmati induced the production of gamma interferon (IFN-γ) and the IFN-γ-inducing cytokines interleukin-12p40 (IL-12p40) and tumor necrosis factor alpha in human whole blood in vitro. The production of IFN-γ was largely dependent on IL-12. These...

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Detalhes bibliográficos
Main Authors: de Fost, Maaike, Hartskeerl, Rudy A., Groenendijk, Martijn R., van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Antibodies and Mediators of Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150539/
https://ncbi.nlm.nih.gov/pubmed/12626464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.10.2.332-335.2003
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