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Clearance of Virulent but Not Avirulent Rhodococcus equi from the Lungs of Adult Horses Is Associated with Intracytoplasmic Gamma Interferon Production by CD4(+) and CD8(+) T Lymphocytes

Rhodococcus equi is a gram-positive bacterium that infects alveolar macrophages and causes rhodococcal pneumonia in horses and humans. The virulence plasmid of R. equi appears to be required for both pathogenicity in the horse and the induction of protective immunity. An understanding of the mechani...

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Main Authors: Hines, Stephen A., Stone, Diana M., Hines, Melissa T., Alperin, Debby C., Knowles, Donald P., Norton, Linda K., Hamilton, Mary J., Davis, William C., McGuire, Travis C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC150533/
https://ncbi.nlm.nih.gov/pubmed/12626444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.10.2.208-215.2003
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