Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by a chronic inflammatory process, in which the pro-inflammatory cytokine Tumor Necrosis Factor (TNF)-α is considered to play a role. In the present study the putative involvement of TNF-α gene polymorphisms in pathogenesis of...

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Detalhes bibliográficos
Main Authors: Küçükaycan, Mehmet, Van Krugten, Michiel, Pennings, Herman-Jan, Huizinga, Tom WJ, Buurman, Wim A, Dentener, Mieke A, Wouters, Emiel FM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150514/
https://ncbi.nlm.nih.gov/pubmed/12537602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/rr194
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