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Methotrexate treatment of squamous-cell head and neck cancers: dose-response evaluation.

Seventy-two patients with advanced squamous-cell carcinomas of the head and neck were randomised to receive weekly intravenous methotrexate at doses of either 50 mg/m2 (low dose), 500 mg/m2 (medium dose), or 5 g/m2 (high dose). Patients who failed to respond after four treatments at their initial do...

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Detalhes bibliográficos
Main Authors: Woods, R L, Fox, R M, Tattersall, M H
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1504451/
https://ncbi.nlm.nih.gov/pubmed/6781586
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