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Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6

Cdc42 is a small GTPase that is required for cell polarity establishment in eukaryotes as diverse as budding yeast and mammals. Par6 is also implicated in metazoan cell polarity establishment and asymmetric cell divisions. Cdc42·GTP interacts with proteins that contain a conserved sequence called a...

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Autori principali: Garrard, Sarah M., Capaldo, Christopher T., Gao, Lin, Rosen, Michael K., Macara, Ian G., Tomchick, Diana R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC150343/
https://ncbi.nlm.nih.gov/pubmed/12606577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg110
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