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The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo

Hsp90 is required for the normal activity of steroid receptors, and in steroid receptor complexes it is typically bound to one of the immunophilin-related co-chaperones: the peptidylprolyl isomerases FKBP51, FKBP52 or CyP40, or the protein phosphatase PP5. The physiological roles of the immunophilin...

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Bibliografiske detaljer
Main Authors: Riggs, Daniel L., Roberts, Patricia J., Chirillo, Samantha C., Cheung-Flynn, Joyce, Prapapanich, Viravan, Ratajczak, Thomas, Gaber, Richard, Picard, Didier, Smith, David F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC150341/
https://ncbi.nlm.nih.gov/pubmed/12606580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg108
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