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Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells

The [URE3] phenotype in Saccharomyces cerevisiae is caused by the inactive, altered (prion) form of the Ure2 protein (Ure2p), a regulator of nitrogen catabolism. Ure2p has two functional domains: an N-terminal domain necessary and sufficient for prion propagation and a C-terminal domain responsible...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Komar, Anton A., Lesnik, Thierry, Cullin, Christophe, Merrick, William C., Trachsel, Hans, Altmann, Michael
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150336/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg103
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