Cytotoxic Cyplasin of the Sea Hare, Aplysia punctata, cDNA Cloning, and Expression of Bioactive Recombinants in Insect Cells

A 56-kDa protein isolated from the mucus of the European sea hare Aplysia punctata shows a preferential toxicity to autonomously growing transformed mammalian cells. Cell death induced by this protein differs from both apoptosis and necrosis. The cytotoxic effects are irreversible and become apparen...

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Bibliografiske detaljer
Main Authors: Petzelt, Christian, Joswig, Gaby, Stammer, Hermann, Werner, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503318/
https://ncbi.nlm.nih.gov/pubmed/11922391
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