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Glucocorticoids and Polyamine Inhibitors Synergize to Kill Human Leukemic CEM Cells

Glucocorticoids are well-known apoptotic agents in certain classes of lymphoid cell malignancies. Reduction of intracellular polyamine levels by use of inhibitors that block polyamine synthesis slows or inhibits growth of many cells in vitro. Several such inhibitors have shown efficacy in clinical t...

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Main Authors: Miller, Aaron L, Johnson, Betty H, Medh, Rheem D, Townsend, Courtney M, Thompson, E Brad
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503311/
https://ncbi.nlm.nih.gov/pubmed/11922393
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