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Glucocorticoids and Polyamine Inhibitors Synergize to Kill Human Leukemic CEM Cells

Glucocorticoids are well-known apoptotic agents in certain classes of lymphoid cell malignancies. Reduction of intracellular polyamine levels by use of inhibitors that block polyamine synthesis slows or inhibits growth of many cells in vitro. Several such inhibitors have shown efficacy in clinical t...

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Detalhes bibliográficos
Main Authors: Miller, Aaron L, Johnson, Betty H, Medh, Rheem D, Townsend, Courtney M, Thompson, E Brad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503311/
https://ncbi.nlm.nih.gov/pubmed/11922393
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