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Identification of Semaphorin3B as a Direct Target of p53

A cDNA microarray analysis indicated that Semaphorin3B (Sema3B), a gene whose product is involved in axon guidance and axonal repulsion, is inducible by p53. Introduction of exogenous p53 into a glioblastoma cell line lacking wild-type p53 (U373MG) dramatically induced expression of Sema3B mRNA. An...

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Bibliographic Details
Main Authors: Ochi, Kensuke, Mori, Toshiki, Toyama, Yoshiaki, Nakamura, Yusuke, Arakawa, Hirofumi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503310/
https://ncbi.nlm.nih.gov/pubmed/11922394
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