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Activation of the Small GTPase Rac Is Sufficient to Disrupt Cadherin-dependent Cell-Cell Adhesion in Normal Human Keratinocytes

To achieve strong adhesion to their neighbors and sustain stress and tension, epithelial cells develop many different specialized adhesive structures. Breakdown of these structures occurs during tumor progression, with the development of a fibroblastic morphology characteristic of metastatic cells....

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Autors principals: Braga, Vania M.M., Betson, Martha, Li, Xiaodong, Lamarche-Vane, Nathalie
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15031/
https://ncbi.nlm.nih.gov/pubmed/11071901
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