Poorly Differentiated Breast Carcinoma is Associated with Increased Expression of the Human Polycomb Group EZH2 Gene

Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. We describe the expression of five PcG genes (BMI-1, RING1, HPC1, HPC2, and EZH2) in normal breast tissues, invasive breast carcinomas, and their precursors. Members of the HPC-HPH/PRC1...

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Hlavní autoři: Raaphorst, Frank M., Meijer, Chris J. L. M., Fieret, Elly, Blokzijl, Tjasso, Mommers, Ellen, Buerger, Horst, Packeisen, Jens, Sewalt, Richard A. B., Otte, Arie P., van Diest, Paul J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2003
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502571/
https://ncbi.nlm.nih.gov/pubmed/14965441
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