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H2AX phosphorylation within the G(1) phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

The variant histone H2AX is phosphorylated in response to UV irradiation of primary human fibroblasts in a complex fashion that is radically different from that commonly reported after DNA double-strand breaks. H2AX phosphorylation after exposure to ionizing radiation produces foci, which are detect...

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Autors principals: Marti, Thomas M., Hefner, Eli, Feeney, Luzviminda, Natale, Valerie, Cleaver, James E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502549/
https://ncbi.nlm.nih.gov/pubmed/16788066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603779103
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