Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa

The sst1 locus has been identified in a mouse model to control resistance and susceptibility of Mycobacterium tuberculosis infection. Subsequent studies have now identified Ipr1 (intracellular pathogen resistance 1) to be the gene responsible. Ipr1 is encoded within the sst1 locus and is expressed i...

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Main Authors: Tosh, Kerrie, Campbell, Sarah J., Fielding, Katherine, Sillah, Jackson, Bah, Boubacar, Gustafson, Per, Manneh, Kebba, Lisse, Ida, Sirugo, Giorgio, Bennett, Steve, Aaby, Peter, McAdam, Keith P. W. J., Bah-Sow, Oumou, Lienhardt, Christian, Kramnik, Igor, Hill, Adrian V. S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502463/
https://ncbi.nlm.nih.gov/pubmed/16803959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603340103
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